Racemization: A major inconvenience of all the resolution processes is that the maximum theoretical yield is only 50%, since both enantiomers are present in equal amounts in the racemic mixture. This requires to couple the resolution process to another one called racemization. Here, the unwanted enantiomer is again converted to the racemic mixture. This is usually the step that defines the economics of the process. If there is too much decomposition during the racemization, the process might be unviable.
For more information, contact us.